Before conducting your search it is useful to focus your research question by thinking about the following aspects of your proposed protocol:
In addition it would be good to think about or gether the following information:
Note: Searches for articles illustrating Reduction and Refinement should be similar to a literature search you would perform to find all the research that has been done on your topic. It should be a broad search that looks for different methods that have been used to conduct similar research.
Search examples are from Chilov, Marina, Matsoukas, Konstantina, Ispahany, Nighat, Allen, Tracy Y. and Lustbader, Joyce W.(2007)'Using MeSH to Search for Alternatives to the Use of Animals in Research',Medical Reference Services Quarterly,26:3,55 — 74
Understanding how to correctly use Boolean operators to construct your search is important!
|AND||Narrows search to only items containing both terms; best for combining 2 concepts||heart attack AND aspirin|
|OR||Broadens search to items containing any terms; best for combining synonyms||heart attack OR myocardial infarction|
|NOT||Narrows search to items containing 1 term but not another; use with caution||dolphins NOT football|
Want to include all forms of a word in your search without typing them all in? Truncation can help! Most databases allow you to insert a symbol at the end of the root of a word to indicate that you would like it to retrieve any records with that word plus any ending it could have.
disease* will retrieve: disease, diseases, diseased, etc.
reduc* will retrieve: reduce, reduces, reduction, etc.